Enhanced oxidizability of ubiquinol andα-tocopherol during lovastatin treatment
نویسندگان
چکیده
منابع مشابه
Effects of Lovastatin Therapy on Susceptibility of LDL to Oxidation During a-Tocopherol Supplementation
A randomized, double-masked, crossover clinical trial was carried out to evaluate whether lovastatin therapy (60 mg daily) affects the initiation of oxidation of low density lipoprotein (LDL) in cardiac patients on a-tocopherol supplementation therapy (450 IU daily). Twenty-eight men with verified coronary heart disease and hypercholesterolemia received a-tocopherol with lovastatin or with dumm...
متن کاملEffects of lovastatin therapy on susceptibility of LDL to oxidation during alpha-tocopherol supplementation.
A randomized, double-masked, crossover clinical trial was carried out to evaluate whether lovastatin therapy (60 mg daily) affects the initiation of oxidation of low density lipoprotein (LDL) in cardiac patients on alpha-tocopherol supplementation therapy (450 IU daily). Twenty-eight men with verified coronary heart disease and hypercholesterolemia received alpha-tocopherol with lovastatin or w...
متن کاملUbiquinone supplementation during lovastatin treatment: effect on LDL oxidation ex vivo.
A randomized, double-masked, placebo-controlled cross-over trial was carried out to evaluate whether ubiquinone supplementation (180 mg daily) corrects impaired defence against initiation of oxidation of low density lipoprotein (LDL) related to effective (60 mg daily) lovastatin treatment. Nineteen men with coronary heart disease and hypercholesterolemia received lovastatin with or without ubiq...
متن کاملEffects of alpha-tocopherol associated with lovastatin on brain tissue and memory function in SHRSPs
Strokes are preceded by oxidative stress and inflammation, two processes linked to atherosclerosis and hypertension. Statins have been widely employed to control atherosclerosis; however, there could be neurological implications to its use—including cognitive impairment. Thus,we aimed to determine whether alpha-tocopherol is capable of reversing the neurological side effects of statins and enha...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1997
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(97)00609-1